H. Robert Superko, MD,
FACC, FAHA world renowned for his work
in metabolic heart disease diagnosis and
treatment, and genomics, has joined Saint
Joseph's Translational Research Institute
as executive director, Center for Genomics
and Human Health. Dr. Superko and his
team will develop and conduct research
studies that identify patients genetic
susceptibility to heart disease, cancer
and other chronic disease states and,
most importantly, translate those findings
into individualized treatment programs
based on the person's unique genetic makeup.
Genomics, or the ability
to tailor treatment specifically to a
patient based on their genetic makeup
and the makeup of their disease, is the
future of medicine, and Robert Superko
is one of the world's leaders in the field,
says Nicolas Chronos, MD, president of
the Saint Joseph's Translational Research
Institute. He will develop protocols for
physicians that can be used around the
world to provide patient's with the most
advanced, targeted therapy for specific
diseases.
Saint Joseph's Research
Institute and the Translational Research
Institute are engaged in pre-clinical
and clinical research, bench to bedside
medicine, that offers rapid translation
of research laboratory findings into patient
treatments. Dr. Superko is credited with
being the first to develop individualized
heart disease treatment based on 12 different
subclasses of cholesterol-carrying particles
that contribute to heart failure and death.
Through blood tests, physicians can identify
a patient's individual risk factors for
heart disease and prescribe the proper
treatment, established by federally-funded
research, that significantly reduces the
risk of heart attack and death.
"Saint Joseph's
is unique in its research capabilities
and programs as a non-academic institution
in Atlanta and around the country",
says Dr. Chronos. Research and trials
conducted here may be translated to more
effective treatments that could reduce
the costs of health care.
The Center for Genomics
and Human Health is the first and only
such program of its kind in Georgia. Dr.
Superko is currently working with the
Gwinnett County Fire Department on a federally-funded
Firefighter and Heart Disease program.
He also is creating a Cardiogenomic Registry
and working to establish the Family Heart
Disease Program at Saint Joseph's.
A family history of
heart disease and genetic tests have been
found to be very high predictors of heart
disease and recent scientific advances
allows this knowledge to be translated
into practical patient care. By applying
lessons learned at Stanford University
and the University of California, Berkeley,
Dr. Superko can identify individuals at
very high risk for coronary heart disease
(CHD), particularly within families. With
this knowledge, appropriate early interventions
can be taken to prevent a nonfatal or
fatal event. Saint Joseph's is the first
hospital in the United States to have
a clinically-viable Family Heart Disease
Clinic, staffed by cardiology Fellows
associated with the Saint Joseph's Heart
and Vascular Institute (SJHVI).